The protection from malaria-associated ALI fully correlated with a significant decrease in VEGF levels in circulation (66% decrease between mice developing malaria-associated ALI and non-ALI in the group receiving LacZ-adenoviruses and 63% decrease between malaria-associated ALI-developing mice receiving LacZ-adenoviruses and non-ALI mice receiving sFLT1-adenoviruses, P<0.05 or P<0.005, respectively) (Figure 7D). Here, VEGFA is linked to malaria.