FTO and obesity due to melanocortin 4 receptor deficiency: There was also no association observed between 2 FTO polymorphisms (rs9939609 and rs8050136) and obesity, BMI, WC, or diabetes in African-American participants in a nested case-control study of postmenopausal women from the Women's Health Initiative-Observational Study [12], or between FTO variants and either BMI or weight in a genome-wide association study that included a group of 1,160 African-Americans in the discovery sample [13].