CXCL8 and chronic obstructive pulmonary disease: Interesting, in our COPD patients, serum CRP levels were related to concentrations of IL-6 (r = 0.333, p < 0.001), IL-8 (r = 0.125, p = 0.039), fibrinogen (r = 0.356, p < 0.001) and A1AT (r = 0.194, p < 0.001).