BGLAP and hyperinsulinemic hypoglycemia, familial, 4: We previously found that decreases in serum N-terminal propeptide of type 1 collagen (P1NP) levels following acute (3 weeks) E and T deficiency in men were prevented by E but not T, whereas both E and T were able to prevent decreases in serum osteocalcin (OCN) levels.(8)