Mutations of SEDLIN have been reported in patients with spondyloepiphyseal dysplasia tarda (SEDT), an X-linked osteochondrodysplasia that is characterised by short stature, a disproportionate short trunk, barrel-shaped chest, narrowing of the intervertebral disc spaces, platyspondyly, a shortened femoral neck, and early onset secondary osteoarthritis which may require hip replacement before the age of 40 years [7]. This evidence concerns the gene TRAPPC2 and spondyloepiphyseal dysplasia tarda, X-linked.