TRAPPC2 and spondyloepiphyseal dysplasia tarda, X-linked: An assessment of 3 other mammalian cell lines (COS1, HEK293 and HK2) revealed all of them to express SEDLIN (Figure 5B), and as SEDLIN-null cell lines are not available from SEDT patients or a mouse model, we further explored the effects of mutant SEDLINs on the interaction with the transcription factors MBP1, PITX1 and SF1, in yeast cells.