Laminopathies represent a group of rare human hereditary diseases, which are caused by mutations in genes encoding components of the nuclear lamina, including the A- and B-type lamins as well as lamin-associated proteins, e.g. emerin, lamina associated polypeptide (LAP) 2α, or lamin B receptor (LBR) [6], [7]. The gene discussed is LBR; the disease is laminopathy.