The following parameters were independently associated with severe falciparum malaria: serum sodium < 131 mmol/L, CRP > 175 mg/L, LDH > 750 U/L, thrombocytes < 20 × 109/L and leukocytes > 6.5 × 109/L (Table 2). The gene discussed is CRP; the disease is Plasmodium falciparum malaria.