Specifically, the frequency of SD cells in bone marrow samples of the pre transplantation patients ranged from 25.0-46.0% and 29.0-49.0% for TP53 and AML1, respectively, whereas the corresponding values for cancer free individuals ranged respectively from 10.7-23.2% and 12.0-25.5% (Figure 5). This evidence concerns the gene RUNX1 and cancer.