STL-6014 uptake was monitored in mice bearing MDA-MB-231-red fluorescence protein (RFP) breast tumors with and without central necrosis and compared with that of the following compounds: (1) STL-7012, an RGD-free analog; (2) HSA-STL-6014; and (3) HSA-STL-7012. The gene discussed is ALB; the disease is breast neoplasm.