Since then, increased serum levels of TGF-β1 have been implicated as a prognostic marker of advanced disease and poor prognosis in multiple cancer types such as gastric carcinoma, colorectal cancer, bladder carcinoma, prostate cancer, breast cancer, lung cancer, esophageal adenocarcinoma, and melanoma [36–44]. The gene discussed is TGFB1; the disease is prostate carcinoma.