Eighty-two sera from SSc patients were further analysed for co-occurrence of anti-CENP-A and other aabs (anti-Scl 70, -CENP, -U1-RNP, -SS-A/Ro60, -Ro52, -Ro60, -SS-B/La, -Sm). The gene discussed is CENPA; the disease is systemic sclerosis.