CENPA and systemic lupus erythematosus: Comparison of ACA (CENP-A or CENP-B) positive SLE patients with the entire SLE cohort revealed a statistically relevant increased prevalence of affected males (P = 0.0103), joint involvement (Jaccoud deformity) (P = 0.0006) and anti-phospholipid syndrome (P = 0.0157).