IFI30 and autoimmune disease: Absence of lysosomal thiol reductase GILT can affect immune responses to viral [13], [14], tumor [15], [16], and parasite antigens (Dr. N. Nanda and Dr. M. Maric, unpublished), and can affect the development of autoimmune diseases, such as experimental allergic encephalomyelitis (Dr. N. Ruddle, unpublished data) and diabetes [17].