Other possible candidates are the type V collagen genes COL5A1and COL5A2 involved in Ehlers-Danlos syndrome (EDS) [9], fibrillin-1 gene (FBN1) responsible for Marfan syndrome [10], PAX6 associated with aniridia [11] and FOXC1 associated with abnormal ocular development [12]. This evidence concerns the gene FBN1 and Marfan syndrome.