CD4 and infection: Verhoeven D et al., using rhesus macaques infected with SIV and treated with FTC (emtricitabine)/PMPA at 1 weeks of infection over a period of 30 weeks, showed, despite major suppression of viral RNA levels in GALT, that ART led to a restoration of CD4+T cell levels in this tissue, in comparison with placebo-treated animals [25], [7].