For this, C8166-SEAP cells (Fig. 6A) and PBMCs (Fig. 6B) were infected with a replication-competent HIV-1 variant harbouring EGFP and analyzed for binding of annexin V and the podoplanin-specific antibody 18H5 at seven days post infection, when massive cytopathic effect was visible in infected C8166-SEAP cell cultures. The gene discussed is PDPN; the disease is infection.