NFKB1 and lymphoma: These results can be explained biochemical and biologically by different facts: PTX is an effective inhibitor of phosphodiesterase (PD) activity (mainly PD4), and has also been reported to prevent the arrival of the NF-κB to the cellular nucleus by inhibition of the phosphorylation of serine 32 and 36 of the IκB complex in lymphoma and the human monocyte cell line U937 [21,24].