Seed extracts of Eugenia jambolana enhanced insulin secretion from isolated islets of STZ-induced diabetic rats in the presence of 10 mM glucose [82]; eupatilin, a flavone from Artemisia princes, elevated pancreatic insulin concentration in type 2 diabetic mouse model (db/db) [83]; and aqueous extract from Abutilon indicum, a plant used as traditional medicine in Thailand, stimulated insulin secretion from isolated rat islets and INS-1E cells [84]. The gene discussed is INS; the disease is type 2 diabetes mellitus.