Compared with the men excluded (missing HFE genotype; n = 112), the men in our study sample were younger (66 vs. 70 years), had lower tibia and patella bone lead levels (19 vs. 22 μg/g and 26 vs. 32 μg/g for tibia and patella lead levels, respectively), and were less likely to have diabetes and use hypertension medications than those excluded (6.1% vs. 12.5% and 8.5% vs. 16.9% for diabetes prevalence and use of hypertension medications, respectively. This evidence concerns the gene HFE and diabetes mellitus.