CD40 and systemic lupus erythematosus: SLE mature BM mDCs expressed higher levels of DC-SIGN (SLE versus controls = 45.877 ± 11.245 versus 18.710 ± 11.521; P < 0.05), CD86 (SLE versus controls = 60.243 ± 22.651 versus 29.305 ± 10.987; P < 0.01) and CD80 (SLE versus controls = 40.601 ± 15.245 versus 20.970 ± 5.445; P < 0.01) but lower levels of CD40 (SLE versus controls = 20.972 ± 9.855 versus 28.599 ± 4.847; P < 0.05) than controls (Figure 2e).