SLE mature BM FLDCs expressed higher levels of DC-SIGN (SLE versus controls = 12.711 ± 1.104 versus 1.595 ± 0.424; P < 0.01), CD40 (SLE versus controls = 9.969 ± 5.729 versus 2.601 ± 1.582; P < 0.05) and CD45RA (SLE versus controls = 44.950 ± 11.225 versus 29.352 ± 9.699; P < 0.01) than normal controls. This evidence concerns the gene CD40 and systemic lupus erythematosus.