IL10 and Cowden disease: The IL10-1087 polymorphism has also been shown to be associated with differing levels of IgA anti-endomyseal and anti-tissue transglutaminase antibodies in CD patients [16], while recombinant human interleukin 10 has been shown to suppress gliadin dependent T-cell activation in ex vivo cultured coeliac intestinal mucosa [18].