CAPN10 and type 2 diabetes mellitus: The difference in the association between CAPN10 variants with increased risk of T2D between populations (Mexican Americans, northern-Europeans, Pima Indians) may be attributed to the presence of multiple susceptibility alleles at CAPN10 locus, to different linkage disequilibrium patterns of between these variants (and hence haplotypes and haplotype combinations), racial/ethnic differences in the distribution of CAPN10 variants, multiple hypothesis testing, and to inadequate statistical power in a number of these studies, which has likely overestimated this genetic association.