Ten of these genes (WDR67, RFXAP, RP11-50D16.3, CAB39L, THSD1, SPRY2, TGDS, CLDN10, SLC10A2, CD33L3) have been reported changed in tumor tissues, while only 2 (RP11-50D16.3, SLC10A2) have been reported to appear changed in colorectal cancer. The gene discussed is SIGLEC15; the disease is neoplasm.