TNF and myocardial infarction: This finding agrees with other authors studies which assessed the role of TNFα both in myocardial infarction and in left ventricular remodeling; particularly, it has been found that the levels of late cytokine activation in the noninfarctual region correlate the best with the eventual left ventricular end-diastolic diameter measured at 20 weeks after infarction [7, 8].