For synaptogyrin-3, both N-18 and C-18 antibodies yielded a similar signal, but the N-18 antibody yielded a crisper result though the maximal signal was distinctly weaker compared to AQP6, for which crisp membranous staining was noted in oncocytoma, but not in chRCC. Here, AQP6 is linked to chromophobe renal cell carcinoma.