For synaptogyrin-3, both N-18 and C-18 antibodies yielded a similar signal, but the N-18 antibody yielded a crisper result though the maximal signal was distinctly weaker compared to AQP6, for which crisp membranous staining was noted in oncocytoma, but not in chRCC. This evidence concerns the gene AQP6 and oncocytic adenoma.