To examine whether WP1066 would induce apoptosis in renal cancer cells, Caki-1 and 786-O cells incubated for 24 h with 2.5 or 5 μM WP1066 were double stained with annexin-V and propidium iodide and were analysed by flow cytometry. This evidence concerns the gene ANXA5 and renal carcinoma.