For instance, LASP-1 overexpression was reported to be due to LASP1 gene amplification detected in 12 out of 98 tested whole breast cancer samples (Bieche et al, 1996) while Tomasetto et al detected an amplification of LASP1 only in one (BT-474) out of eight different breast cancer cell lines (Tomasetto et al, 1995b). The gene discussed is LASP1; the disease is breast carcinoma.