As LASP1 gene amplification was reported earlier in one breast cancer cell line (Tomasetto et al, 1995b) and in 40% of crude extracts of lymph nodes derived from metastatic breast cancer (Tomasetto et al, 1995a) and was accounted for the principal cause of LASP-1 overexpression, we also re-analysed the rate of LASP1 gene amplification in individual micro-dissected primary breast cancer cells. The gene discussed is LASP1; the disease is breast cancer.