Strong expression of P-selectin in the mesangium, in the glomerular capillaries and Bowman's capsule was also found in other human and experimental glomerulonephritis [41-43], and the expression of P-selectin in the glomeruli was suggested to be critical for control of the severity and diversity of glomerular lesioning [12,44]. The gene discussed is SELP; the disease is glomerulonephritis.