The network is associated with functions linked to immunological disease, cancer, renal and urological diseases, and concerns a series of six canonical pathways, including purine metabolism, oxidative phosphorylation, glucocorticoid receptor signaling, IL-8 signaling, hepatic fibrosis/hepatic stellate activation and leukocyte extravasation signaling. The gene discussed is CXCL8; the disease is urinary system disorder.