Five genes (ATF3, BCKDHA, FGFR3, RRM2 and SDC1) are altered by cyclin D1b alone and six (BNIP3, CBS, CST3, HCLS1, RAN, SQSTM1) by both cyclins D1b and K. Those findings question the relevance of cyclin D1b expression in MM pathogenesis. The gene discussed is CBS; the disease is Miyoshi myopathy.