In order to evaluate the potential contribution of CCL20/CCR6 in development and progression of PCA, we analyzed the mRNA and protein expression profiles of the CCL20/CCR6 system in patients with PCA as well as in patients with PA and CP, which represent pre-malignant diseases which often precede the formation of pancreatic malignancies [27,28]. This evidence concerns the gene CCR6 and posterior cortical atrophy.