TOP2A and neoplasm: In summary, correlation of mRNA and copy number identified numerous breast cancer tumor suppressor genes and oncogenes, such as STAT5A, SNIP, ZNF217, TOP2A, BCL2, PAK1, PER3, CCND1, NME1, PPAPDC1B, LSM1, IL17RB and FGFR1, to be significantly correlated in HER2+ tumors.