Analysis of gene expression of CTNNB1 and TCF/LEF transcription targets, using Oncomine [27] and GeneSpring software and publicly available microarray datasets for normal (non-neoplastic or benign) vs cancer prostate tissue, showed that the expression of almost all Wnt/β-catenin/TCF targets analyzed, except c-myc, was decreased in prostate cancer (Fig. S3). The gene discussed is HNF4A; the disease is cancer.