Similarly, in animal models of ischemia, stroke, hypertension, stress, and Parkinson's disease, which are also characterized as pro-inflammatory conditions, PPAR-γ agonists provide significant neuroprotection [100], [101], [102], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112]. The gene discussed is PPARG; the disease is stroke disorder.