TLR9 and infection: Bafica and collaborators have shown that doubly deficient Tlr2−/− Tlr9−/− mice, although more susceptible than the single TLR2- or TLR9-deficient mice, do not display the acute mortality exhibited by Myd88−/− mice, suggesting that additional TLR/IL-1R family members are involved in the protection against infection with T. cruzi in mice [6].