Assessment of the metastatic burden in mice inoculated with cell lines originated from non-metastatic CSML0 adenocarcinoma cell line, (CSML0-RANTES vs CSML0-mock) confirmed the influence of RANTES in stimulation of metastases, although being statistically insignificant, p = 0.2 for lung and p = 0.32 for liver metastases (Fig. 6C). This evidence concerns the gene CCL5 and adenocarcinoma.