Whereas expression of cyclin D1 in adenomas from ApcΔ14/+FHL2−/− mice showed significant higher level than that in tumors from ApcΔ14/+FHL2+/+ mice, no significant difference of c-myc expression was observed in adenomas between ApcΔ14/+FHL2+/+ and ApcΔ14/+FHL2−/− animals (Fig. 3B). The gene discussed is CCND1; the disease is adenoma.