ARID4A and squamous cell carcinoma: ARID4A mRNA levels were decreased (≥ 2-fold) in almost half of the squamous cell carcinomas samples (-1.04 to -6.9-fold change, 23 of 47 samples, i.e., 49%) and were increased in some of these samples (1.51 to 6.26-fold change, 7 of 47 samples, i.e., 15%) (Figure 4B).