On the other hand, an NIHSS score of ≤ 6 is related with a good functional capacity.[11] In their study, Tomita et al. found that there is a positive correlation between the NIHSS score and BNP levels in stroke patients.[33] However, Giannakoulas et al. did not find a correlation between NIHSS and BNP levels.[34] In our study, we did not find a significant correlation between NIHSS and plasma BNP levels. This evidence concerns the gene NPPB and Stroke.