To estimate the quality of the expression profiling data, we performed immunohistochemical analyses of expression for two arbitrarily chosen gene products, one overexpressed in cyst epithelium and tumor compared to surface epithelium (TOP2A) and one underexpressed in cyst and tumor compared to surface epithelium (FOS), using 56 pathologically normal ovaries (Figure 3). This evidence concerns the gene TOP2A and cyst.