It should be noted that these samples contain a high degree of cellular heterogeneity, such that the detection of moderate levels of α-SMA in one normal sample (lane 1) may represent the presence of contaminating vascular smooth muscle cells within that biopsy, and the detection of a small amount of E-cadherin in one tumor sample (lane 6) probably reflects the presence of a small amount of normal pancreas within that sample. This evidence concerns the gene ACTA1 and neoplasm.