The expression of SOCS2 mRNA was found to decrease with increasing NPI; NPI-1 vs. NPI-3 [mean copy number 495133 vs. 12414, 95% CI (39141, 926297), p = 0.033], but was found to significantly increase with higher tumour grade; grade 2 vs. grade 3 [mean copy number 44859 vs. 512760, 95% CI (-921508, -14293), p = 0.043]. This evidence concerns the gene SOCS2 and neoplasm.