SOCS4 and neoplasm: The expression of SOCS4 mRNA was demonstrated to decrease with increasing TNM stage; TNM-1 vs. TNM-4 [mean copy number 384 vs. 1.51, 95% CI (73, 691.9), p = 0.016], and TNM-2 vs. TNM-4 [mean copy number 180 vs. 1.51, 95% CI (1, 355.5), p = 0.049] but did not significantly differ with tumour grade or with NPI.