NFKB1 and plasma cell myeloma: Constitutive activation of NF-κB has frequently been observed in follicular lymphoma [53,54], DLBCL [55], mucosa-associated lymphoid tissue (MALT) lymphoma [56], multiple myeloma (MM) [57], and mantle-cell lymphoma (MCL), as well as MCL cell lines, in which inhibition of this constitutive activation induces growth arrest and apoptosis [58-60].