CRP and herpes zoster: A health economic evaluation of the new live attenuated vaccine against herpes zoster in England and Wales was recently published by Van Hoek et al. [8] The Van Hoek et al. model employs a different categorisation of HZ/PHN pain states by including a state of clinically relevant pain (CRP) to characterize both moderate and severe pain, while it assumes a limited duration of efficacy with the use of a waning rate,.