CXCR1 and neoplasm: There was a positive association between survival and tumour islet CXCR2 (p = 0.02), CXCR3 (p = 0.003) and CCR1 (p < 0.001) density, but no significant associations between survival and tumor islet CXCR1, CXCR4 and CXCR5 density (Fig 3A-F).