WT1 and leukemia: Although WT1 is expressed mainly in the urogenital system during development and in the central nervous system, bone marrow, lymph nodes, and gonads in adulthood [33,34], many studies have shown elevated WT1 expression in diverse cancer types [29], including leukemia [35-37]., breast [29,38,39], ovarian [40], mesothelioma and pulmonary adenocarcinomas [30].