MYC and neoplasm: Myc represses the transcription of key growth control, differentiation and tumor suppressor genes including GAS1, p15INK4, p21CIP1, p27KIP1, p57KIP2, growth arrest and DNA damage 34 (GADD34), GADD45, C/EBPα and GADD153 (C/EBPζ) [25,28-42].