Angiopoietin-2 and ICAM-1 were significantly correlated with both ADMA (rs = 0.48 and 0.42 respectively; p<0.001; Table 3), and SDMA (rs = 0.54 and 0.52; p<0.001), and this was also apparent in the subgroup of SM patients; Table 3. This evidence concerns the gene ANGPT2 and systemic mastocytosis.