Similarly the odds ratios for the respective obesity risk effect alleles did not vary strongly by group (children and adolescents vs. adults) with point estimates ranging between 1.35–1.45 (FTO), 1.35–1.45 (TMEM18) and 1.10–1.19 (SDCCAG8). This evidence concerns the gene SDCCAG8 and obesity due to melanocortin 4 receptor deficiency.