SNAI1 and malignant colon neoplasm: We used 2D-DIGE electrophoresis combined with MALDI-TOF-TOF and ESI-linear ion trap mass spectrometry to compare the pattern of proteins present in nuclear extracts from human colon cancer SW480-ADH cells expressing a retrovirally-transduced Snail1 cDNA (Snail1 cells) with that of mock-infected cells (Mock cells).