IGF1 and neoplasm: Another identified target of miR-185 was PTPN13 (also a predicted miR-185 target in miRBase: http://microrna.sanger.ac.uk/), which is a Fas-associated protein tyrosine phosphatase and putative tumor suppressor gene that can inhibit PI3K/AKT signaling, suppress the influence of insulin-like growth factor-I on cell survival and induce apoptosis [71].